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Study of DLTH inhibiting RA by regulating immune function and cartilage degradation / 中国药理学通报
Chinese Pharmacological Bulletin ; (12): 624-630, 2021.
Article en Zh | WPRIM | ID: wpr-1014409
Biblioteca responsable: WPRO
ABSTRACT
Aim To observe the immune regulation and cartilage protection of dexamethasone-loaded thermosensitive hydrogel (DLTH) on rheumatoid arthritis (RA) rats via conceiving a newly injectable sustained DLTH with chitosan-glycerin-borax as carrier. Methods Thirty rats were randomly divided into three groups, namely control, model and DLTH group. RA model was established through immune induction in model and DLTH group. From the 12th day, rats of DLTH group were injected with 40 (jlL DLTH (1 mg · kg
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Texto completo: 1 Índice: WPRIM Idioma: Zh Revista: Chinese Pharmacological Bulletin Año: 2021 Tipo del documento: Article
Texto completo: 1 Índice: WPRIM Idioma: Zh Revista: Chinese Pharmacological Bulletin Año: 2021 Tipo del documento: Article