Bioequivalence study of buthlphthalide injection in Chinese healthy volunteers / 中国临床药理学与治疗学
Chinese Journal of Clinical Pharmacology and Therapeutics
;
(12): 70-76, 2022.
Artículo
en Chino
| WPRIM
| ID: wpr-1014913
ABSTRACT
AIM:
To establish a method to investigate pharmacokinetics and bioequivalence of buthlphthalide injection.METHODS:
An open, randomized, and two-cycle crossover study was conducted in 24 healthy volunteers. Plasma concentrations of buthlphthalide were determined by LC-MS/MS after administering a single dose of reference drug or test drug. Main pharmacokinetic parameters were calculated by Phoenix WinNonlin 6.4 software.RESULTS:
For the test drug and the reference drug, the main pharmacokinetic parameters of flurbiprofen were as follows AUC
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Idioma:
Chino
Revista:
Chinese Journal of Clinical Pharmacology and Therapeutics
Año:
2022
Tipo del documento:
Artículo
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