Clinical observation of pulsed radiofrequency combined with invigorating-kidney activating-blood prescription in the treatment of knee osteoarthritis of kidney deficiency and blood stasis type / 重庆医学

ABSTRACT

Objective To observe the clinical efficacy of pulsed radiofrequency combined with invigorat-ing-kidney activating-blood prescription in the treatment of knee osteoarthritis(KOA)with kidney deficiency and blood stasis.Methods A total of 80 patients with KOA of kidney deficiency and blood stasis type admit-ted to the First Teaching Hospital of Tianjin University of Traditional Chinese Medicine from January 2021 to May 2022 were selected as the research objects.They were divided into control group and treatment group by random number table,with 40 cases in each group.The control group was treated with sodium hyaluronate in-jection in the knee joint cavity,and the treatment group was treated with pulsed radiofrequency combined with invigorating-kidney activating-blood prescription.The clinical efficacy,visual analogue scale(VAS)score,Western Ontario and McMaster University Osteoarthritis Index score(WOMAC score),Lequesnse muscle strength index(Lequesnse index)and serum inflammatory factors tumor necrosis factor(TNF)-α,interleukin(IL)-1β and high-sensitivity C-reactive protein(hs-CRP)were compared between the two groups before and after treatment.Results The total effective rate of the treatment group(92.50％)was higher than that of the control group(82.50％),and the difference was statistically significant(P＜0.05).After treatment,the VAS scores,WOMAC score,Lequesnse index,and the levels of TNF-α,IL-1β,and hs-CRP in two groups were sig-nificantly lower than those before treatment(P＜0.05),and these indexes in the treatment group were signif-icantly lower than those in the control group(P＜0.05).Conclusion Pulsed radiofrequency combined with invigorating-kidney activating-blood prescription has a definite clinical effect on KOA of kidney deficiency and blood stasis type,which can improve knee joint function and reduce serum TNF-α,IL-1β,and hs-CRP levels.