The Efficacy of Electric Nail Grinding with Nail Lacquer in the Treatment of Onychomycosis / 대한피부과학회지

ABSTRACT

BACKGROUND: There is a need for additional effective treatments for onychomycosis. Aggressive debridement has been explored as a therapeutic option for onychomycosis, but rigorously designed studies in this area have been limited. OBJECTIVE: We sought to examine the efficacy of the nail grinder and nail lacquer in the treatment of onychomycosis. We planned the study to determine whether adding aggressive nail grinding to nail lacquer for treating toenail onychomycosis improves the efficacy. METHODS: To provide better delivery of drug to bed and nail plate, we trimmed with electric nail grinder (KHP 3000 Frees(R), Germany), and then applied nail lacquer (Amorolfine HCl, Loceryl(R), Galderma korea). Clinical photo was taken for infected area evaluation. The phototrichogram system (Folliscope, LeadM Corporation, Seoul, Korea) was used for the computer-aided evaluation of the nail plate thickness. RESULTS: Aggressive debridement of infected nail with electric nail grinder made an improvement over the duration of the treatment with nail lacquer. CONCLUSION: Aggressive debridement with an electric nail grinder is likely to be more effective than with a nail file. Electric nail grinder could be adopted as the treatment of onychomycosis. The potential for synergism of electric nail grinder with topical antifungal agent is expected.