A Case of del(16)(q22) in a Patient with Acute Myeloid Leukemia with Complex Karyotype / 대한진단검사의학회지
The Korean Journal of Laboratory Medicine
;
: 329-333, 2010.
Artículo
en Coreano
| WPRIM
| ID: wpr-102103
ABSTRACT
Inversion of chromosome 16 [inv(16)(p13.1q22)] and t(16;16)(p13.1;q22) are associated with acute myelomonocytic leukemia (AMML) with eosinophilia and a favorable prognosis. On the other hand, patients with del(16)(q22) usually present with MDS or chronic myelomonocytic leukemia (CMML), which can evolve to AMML without eosinophilia, and this chromosomal aberration is associated with older age, a complex karyotype, and a poor prognosis. We report a case of AML with del(16)(q22) which showed a complex karyotype, absence of eosinophilia in bone marrow study and a poor response to chemotherapy.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Pronóstico
/
Cromosomas Humanos Par 16
/
Leucemia Mieloide Aguda
/
Daunorrubicina
/
Deleción Cromosómica
/
Hibridación Fluorescente in Situ
/
Citarabina
/
Quimioterapia Combinada
/
Células Precursoras de Monocitos y Macrófagos
/
Cariotipificación
Tipo de estudio:
Estudio pronóstico
Límite:
Humanos
/
Masculino
Idioma:
Coreano
Revista:
The Korean Journal of Laboratory Medicine
Año:
2010
Tipo del documento:
Artículo
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