A Case of Allopurinol Hypersensitivity Syndrome in a Patient with Chronic Renal Failure / 대한신장학회잡지
Korean Journal of Nephrology
;
: 851-855, 2005.
Artículo
en Coreano
| WPRIM
| ID: wpr-102317
ABSTRACT
Allopurinol hypersensitivity syndrome is a rare but life-threatening complication. We here report a case of allopurinol hypersensitivity syndrome manifested with irreVersible change of renal function and severe toxic epidermal necrolysis in a patient with chronic renal faiure. A 29-year-old male patient with chronic renal failure due to chronic glomerulonephritis presented with high fever and skin rash. He had been taking allopurinol for 6 weeks due to asymptomatic hyperuricemia. Blood chemistry showed severe hepatic dysfunction and aggrevated renal function. Skin biopsy revealed consistent findings with allopurinol hypersenstivity syndorme. Allopurinol was discontinued and steroid was instituted. His cutaneous lesion and high fever, and hepatic dysfunction improved but renal function irreversibly progressed in end stage renal failure requiring maintenance hemodialysis treatment.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Piel
/
Biopsia
/
Química
/
Alopurinol
/
Diálisis Renal
/
Síndrome de Stevens-Johnson
/
Hiperuricemia
/
Insuficiencia Renal
/
Exantema
/
Fiebre
Límite:
Adulto
/
Humanos
/
Masculino
Idioma:
Coreano
Revista:
Korean Journal of Nephrology
Año:
2005
Tipo del documento:
Artículo
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