The Changes of IOP during General Anesthesia

ABSTRACT

The effects of general anesthesia on intraocular pressure were studied in 30 patients ranging in age from 15 to 48 years old. The intraocular pressure was measured by the Schiotz tonometer. The patients were divided into 2 groups: thiopental-succinylcholine-intubation (Group 1) and thiopental-vecuronium-intubation(Group 2). The results were as follows: 1) IOPs after thiopental(5 mg/kg) administration were decreased significantly compared with the control value in both group(p<0.05). 2) IOP after succinylcholine administration were elevated, but it was not statistically significant compared with the control value. 3) IOP after vecuronium administration was decreased significantly compared with the control value(p<0.05). 4) IOP after intubation were elevated significantly compared with control value in both groups(p<0.05). 5) IOP at 10 minutes after the induction of general anesthesia was not changed compared with the control value in group 1, but was decreased significantly in group 2(p<0.05).