Effects of Positive Acceleration on Atrial Natriuretic Peptide (ANP), Plasma Renin Activity (PRA), Kidney and Testis / 대한비뇨기과학회지

ABSTRACT

Hypergravity has been shown to affect the human physiology, especially the kidney and heart. The kidney is affected during or after tests on positive acceleration. PRA was increased after positive acceleration. ANP has inverse relationship with renin, which has sodium and water retention. The experiment was design to investigate possible ANP decrease and changes in function and structure of the testis, kidney after exposure to 9G, 120 sec positive acceleratory forces as imposed on rat by the Human Centrifuge. As result, positive radial acceleration has made no change in concentration of ANP in statistically with increasing PRA, After acceleration, the glomerulus of the kidney showed no ischemic changes, but tubule of the kidney showed containing of cast. The seminiferous tubule of the testis showed normal.