Fatal PTLD Accompanied by Rapid Lymphocyte Proliferation in the Early Phase of Allogeneic HSCT / 대한내과학회지
Korean Journal of Medicine
;
: 243-248, 2015.
Artículo
en Inglés
| WPRIM
| ID: wpr-102974
ABSTRACT
Post-transplant lymphoproliferative disorder (PTLD) is a spectrum of clinically and morphologically heterogeneous lymphoid proliferations of various clonal compositions that are observed after hematopoietic stem cell transplantation (HSCT) or solid organ transplantation. The majority of PTLD cases are associated with Epstein-Barr virus (EBV) infection, while overt peripheral blood (PB) or bone marrow (BM) involvement in PTLD is uncommon in early lesions. We report a 38-year-old woman with EBV-related PTLD, with BM and PB involvement, who presented with peripheral lymphocytosis as an early lesion 1 month after haploidentical HSCT for Philadelphia chromosome-positive acute lymphoblastic leukemia was performed during first complete remission. Although PB or BM involvement of PTLD after HSCT is uncommon in early lesions, peripheral lymphocytosis can be an initial presenting manifestation of PTLD, as in this case.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Trasplante
/
Médula Ósea
/
Linfocitos
/
Trasplante de Órganos
/
Herpesvirus Humano 4
/
Trasplante de Células Madre Hematopoyéticas
/
Trasplantes
/
Infecciones por Virus de Epstein-Barr
/
Leucemia-Linfoma Linfoblástico de Células Precursoras
/
Linfocitosis
Límite:
Adulto
/
Femenino
/
Humanos
Idioma:
Inglés
Revista:
Korean Journal of Medicine
Año:
2015
Tipo del documento:
Artículo
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