Accelerating the application of laboratory developed tests based on next-generation sequencing in cancer diagnosis and therapy / 中华检验医学杂志

ABSTRACT

Next-generation sequencing (NGS) has emerged as a valuable tool for cancer diagnosis and treatment. There is an increasing need for clinical application. However, the implementation of related tests in clinical laboratories still faces several issues and challenges. In China, the laboratory developed test (LDT) has recently been introduced, gradually promoting the standardized application of NGS in cancer diagnosis and treatment. This article explores the cruicial factors necessary for the standardized application of LDTs based on NGS in cancer diagnosis and treatment, focusing on three key aspects: clinical needs, self-development, and appropriate utilization.