Research progress on the role of NMDA receptors in migraine / 中风与神经疾病杂志
Journal of Apoplexy and Nervous Diseases
; (12): 1079-1083, 2023.
Article
en Zh
| WPRIM
| ID: wpr-1031748
Biblioteca responsable:
WPRO
ABSTRACT
@#NmethylD-aspartate (NMDA) receptors are ionotropic glutamate receptors that are widely expressed in the central nervous system.Through mediating Ca2+ influx for excitatory synaptic transmission,NMDA receptors play an important role in synaptic plasticity,learning,and memory.Migraine is a common primary headache that brings serious life and mental burdens to patients because of frequent attacks.The pathogenesis of migraine is still unclear.Glutamate and NMDA receptors have been demonstrated to be closely related to the occurrence of migraine.This paper reviews progress on the association of NMDA receptors with migraine and the use of NMDA receptor antagonists for the prevention and treatment of migraine,aiming to provide a reference for the pathogenesis and drug treatment of migraine.
Buscar en Google
Índice:
WPRIM
Idioma:
Zh
Revista:
Journal of Apoplexy and Nervous Diseases
Año:
2023
Tipo del documento:
Article