Correlation of slow wave on quantitative electroencephalography with cognitive dysfunction in patients with temporal lobe epilepsy / 中风与神经疾病杂志

ABSTRACT

@#Objective To investigate the correlation of slow wave on quantitative electroencephalography(QEEG) with cognitive dysfunction. Methods A total of 80 patients with temporal lobe epilepsy who attended The Affiliated Hospital of Chifeng University from January to October 2022 were collected. All patients underwent Montreal Cognitive Assessment(MoCA) and QEEG monitoring to calculate δ wave power and(δ+θ)/(α+β) ratio(DTABR),and statistical analyses were performed. Results There were 40 patients in the temporal lobe epilepsy+cognitive dysfunction group,among whom there were 23 male patients(57.5%) and 17 female patients(42.5%),with a mean age of(48.15±14.85)years,a mean duration of education of 9.43±2.5 years,and a mean duration of medication of 8.35±4.55 years;there were 40 patients in the control group,among whom there were 21 male patients(52.5%) and 19 female patients(47.5%),with a mean age of 50.83±15.58 years,a mean duration of education of 9.45±2.45 years,and a mean duration of medication of 9.23±5.14 years. There were no significant differences in age,sex,education level,and medication years between the cognitive dysfunction group and the normal control group(P>0.05),and there was a significant difference in MoCA score between the cognitive dysfunction group and the normal control group [21±7(5-25) points vs 27±2(26-29) points,Z=-7.738,P<0.05]. The cognitive dysfunction group had significantly higher δ wave power and DTABR than the normal control group(P<0.05). In the patients with temporal lobe epilepsy,cognitive function parameters were correlated with electric power and DTABR on QEEG;cognitive function parameters were negatively correlated with δ wave power and DTABR(P<0.05),while δ wave power was positively correlated with DTABR(P<0.05). Conclusion There is a correlation between slow wave and DTABR on QEEG in patients with temporal lobe epilepsy,suggesting that DTABR can be used as an electric power indicator for cognitive function screening in patients with temporal lobe epilepsy.