Recent advance in amino acid PET combined with MRI in brain gliomas / 中华神经医学杂志

ABSTRACT

Gliomas are the most common primary malignant tumor of the central nervous system, with strong invasion, high disability and mortality, and poor prognosis. The biological distribution characteristics of specific radiopharmaceuticals in amino acid positron emission tomography (PET) could reflect glioma molecular metabolism information, which is complementary to the morphological and functional information of magnetic resonance imaging (MRI); PET combined with MRI play pivotal roles in the diagnosis, biopsy guidance, recurrent monitor and prognosis prediction of gliomas. In this article, the application and research progress of amino acid PET combined with MRI in clinical diagnosis and treatment of brain gliomas are reviewed to provide imaging basis for clinical diagnosis and treatment of gliomas.