Clinical effect of Xueshuantong injection combined with early rehabilita-tion on patients with acute cerebral infarction / 中国现代医生

ABSTRACT

Objective To investigate the clinical effect of Xueshuantong injection combined with early rehabilitation on neurologic function and the influence on blood lipids concentration and high sensitive C-reactive protein in patients with acute cerebral infarction. Methods Totally 120 acute cerebral infarction patients were recruited and randomly di-vided into two groups. The control group was treated with normal therapeutic regimen plus 0.9% normal saline ,the treatment group was given early rehabilitation and xueshuantong injection (0.5g per day), in addition to normal thera-peutic regimen. Treatment duration was 21 days.Their neurologic function impairments and daily living abilities were assessed with the NIHSS and Modified Barthel Index (MBI),The blood lipids concentration and the level of hs-CRP were measured before and after therapy. Results The NIHSS score was significantly lower and the MBI score was sig-nificantly higher in the treatment group on day 7 and 21 after treatment than before treatment(P<0.05).The blood lipids concentration decreased significantly in two groups after drug administration (P<0.05). LDL-C and hs-CRP levels of the treatment group were significantly lower (P<0.05). Conclusion Xueshuantong injection combined with early reha-bilitation may improve neurologic functions and modulate blood lipids and hs-CRP in patients with acute cerebral in-farction.