Investigation of the pathogenic bacteria infection and drug resistance in neonatal intensive care unit (NICU) in 2013 and analysis of the prevention and nursing control measures / 中国现代医生

ABSTRACT

Objective To investigate the situation of the pathogenic bacteria and its drug resistance in neonatal inten-sive care unit (NICU) in 2013 and the prevention and control measures. Methods A total of 1764 cases of neonates treated in neonatal intensive care unit in our hospital in 2013 were selected as research objects and the detection rate and drug resistance of pathogenic bacteria of the 9 types of specimens submitted were compared. Results ①The gram negative bacteria which were tested of 53 cases accounted for 36.30% and gram positive bacteria 93 cases accounted for 63.70%; Among which 3 cases of negative bateria were checked out which accounted for 5.66% and 4 cases of positive bateria were checked out which accounted for 4.30%.The detectable rate was 1.37%(7/510). The contrast difference was obvious(χ2=45.045, P<0.05) compared with that 11.08%(139/1254) in group B.②The drug resistance of Escherichia coli, which had the highest detection rate of pathogenic bacteria, against tetracycline, ampicillin and other common antibiotics was stronger and it was more sensitive to meropenem, chloramphenicol and other drugs. The sensitivity of streptococcus agalactiae, whose detection rate was the second, to chlorine lincomycin, erythromycin and other drugs was lower and was almost no resistance to ampicillin, Cefuroxime sodium and other drugs. The resistance of Staphylococcus aurous and Klebsiella pneumonia against ampicillin was stronger. Such drugs as clinical medicine should be avoided to enhance the curative effect. Conclusion Escherichia coli, no Streptococcus and Staphylococcus aurous are highest NICU detection rate of three kinds of pathogenic bacteria in our hospital in 2013. To effectively re-duce the neonatal cross infection risks, the hospital should further implement the NICU management measures, strengthen disinfection and isolation, monitoring, routine work and so on, strictly follow the principle of aseptic opera-tion, control of the amount of antibiotic drug and create conditions for their newborn resistance and immunity enhance-ment.