Study on the value of GBS culture combined with candida vaginalis detection for predicting preterm premature rupture of membranes / 中国现代医生

ABSTRACT

Objective To investigate the value of combined detection of group B streptococcus (GBS) and vulvovaginal candidiasis (VVC) for predicting preterm premature rupture of membranes (PPROM). Methods A total of 227 pregnant women with PPROM who were hospitalized from August 2016 to August 2017 were selected as observation group. Immediately after admission, patients were given GBS culture and detection of Candida vaginalis. 743 cases of pregnant women with term delivery in the same period were randomly selected as the control group, and were given GBS culture and detection of Candida vaginalis at 35-37 th week of pregnancy. General data such as age, gestational weeks, body mass index, pregnancy time, and parity of the two groups were recorded. The positive rates of GBS and VVC and the relationship between them were observed. Results There was no significant difference in the basic data between the two groups (P>0.05). Among the 227 pregnant women with PPROM, the positive rate of GBS was 9.69％, which was significantly higher than that of the control group (5.11％), and the difference was statistically significant (P<0.05). The positive rate of VVC in the observation group was 25.11％, which was significantly higher than that in the control group (18.71％), and the difference was statistically significant (P<0.05). The positive rate of GBS in pregnant women with positive VVC was 9.69％, higher than that in those with negative VVC, and the difference was statistically significant (P<0.05). Conclusion Positive GBS or VVC can increase the risk of PPROM. It is necessary to routinely perform GBS screening and VVC testing before 35 weeks of gestation to predict the risk of PPROM and treat the patients with positive results.