Sclerosing Angiomatoid Nodular Transformation (SANT) in Spleen: A Case Report
Korean Journal of Pathology
;
: 111-114, 2011.
Artículo
en Inglés
| WPRIM
| ID: wpr-104146
ABSTRACT
Sclerosing angiomatoid nodular transformation (SANT) of spleen is a rare inflammatory tumor-like vascular lesion composed of angiomatoid nodules in a fibrosclerotic background. We report herein on a case of SANT in the spleen with its pathologic features, and review the related literature. A 50-year-old woman presented with mild left upper quadrant discomfort and tenderness and she showed a 6 cm-sized solitary splenic mass on computed tomography. She underwent laparoscopic splenectomy. Grossly, the spleen showed a well circumscribed round-shaped solid mass with multinodular hemorrhagic surfaces. Microscopically, the mass consisted of multiple angiomatoid nodules surrounded by collagen bundles with fibroblasts and a lymphoplasma cell infiltration. Immunohistochemically, the cells of the angiomatoid nodules were positive for CD31, CD30, CD34, alpha-smooth muscle actin, and VWF-VIII, but they were negative for CD8, anaplastic lymphoma kinase protein, and D2-40. The patient has been under close follow-up without recurrence.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Fosfotransferasas
/
Recurrencia
/
Bazo
/
Esplenectomía
/
Estudios de Seguimiento
/
Actinas
/
Colágeno
/
Proteínas Tirosina Quinasas Receptoras
/
Molécula-1 de Adhesión Celular Endotelial de Plaqueta
/
Fibroblastos
Tipo de estudio:
Estudio observacional
/
Estudio pronóstico
Límite:
Femenino
/
Humanos
Idioma:
Inglés
Revista:
Korean Journal of Pathology
Año:
2011
Tipo del documento:
Artículo
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