Cloning a new allele form of bovine TNF-alpha
Journal of Veterinary Science
;
: 139-141, 2001.
Artículo
en Inglés
| WPRIM
| ID: wpr-104742
ABSTRACT
Although little is known on the function of gammadelta T lymphocytes, there is increasing evidence that gammadelta T lymphocytes are early responders and modulators of immune responses against pathogens and cytokines such as IL-2, IL-7, IL-15 and TNF-alpha. To study the role TNF-alpha on gammadelta T lymphocytes, we cloned bovine TNF-alpha. Sequence analysis revealed that a new allele form of bovine TNF-alpha was cloned which has 3 additional nucleotide sequences as well as 3 nucleotide substitutions compared with previously reported bovine TNF-alpha. Further studies are needed to document the functional significance of a new allele form of TNF-alpha in cattle.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Datos de Secuencia Molecular
/
Secuencia de Bases
/
Linfocitos T
/
Biblioteca de Genes
/
Alineación de Secuencia
/
Secuencia de Aminoácidos
/
Factor de Necrosis Tumoral alfa
/
Receptores de Antígenos de Linfocitos T gamma-delta
/
Clonación Molecular
/
Alelos
Límite:
Animales
Idioma:
Inglés
Revista:
Journal of Veterinary Science
Año:
2001
Tipo del documento:
Artículo
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