A case of Cowden's syndrome associated with Lhermitte-Duclos disease / 대한내과학회지

ABSTRACT

Cowden's disease, or multiple hamartoma syndrome, is an uncommon autosomal dominant condition characterized by mucocutaneous lesions and systemic malignancies. Lhermitte-Duclos disease, or dysplastic gangliocytoma of the cerebellum, is a rare cerebellar lesion that can cause mass effects in the posterior fossa. It may occur sporadically, or in association with Cowden's syndrome. We report a case of Cowden's disease associated with Lhermitte-Duclos disease in a 49-year-old man who underwent a routine checkup