Transplant Graft Vasculopathy: An Emerging Target for Prevention and Treatment of Renal Allograft Dysfunction
Yonsei Medical Journal
;
: 1053-1058, 2004.
Artículo
en Inglés
| WPRIM
| ID: wpr-107012
ABSTRACT
Maintenance of healthy endothelium is essential to vascular homeostasis, and preservation of endothelial cell function is critical for transplant allograft function. Damage of microvascular endothelial cells is now regarded as a characteristic feature of acute vascular rejection and chronic allograft nephropathy, which is an important predictor of graft loss and is often associated with transplant vasculopathy. In this review, we will discuss the role of microvascular endothelium, in renal allograft dysfunction, particularly as it relates to markers of endothelial dysfunction and endothelial repair mechanisms. We also discuss the potential for therapies targeting endothelial dysfunction and transplant graft vasculopathy.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Trasplante Homólogo
/
Enfermedades Vasculares
/
Trasplante de Riñón
/
Riñón
Límite:
Humanos
Idioma:
Inglés
Revista:
Yonsei Medical Journal
Año:
2004
Tipo del documento:
Artículo
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