Tranexamic Acid-Induced Acute Renal Cortical Necrosis in Post-Endoscopic Papillectomy Bleeding
Clinical Endoscopy
;
: 609-613, 2017.
Artículo
en Inglés
| WPRIM
| ID: wpr-10729
ABSTRACT
Acute renal failure can be the result of acute renal cortical necrosis (RCN), which commonly occurs from complications occurring during pregnancy. RCN is rarely caused by medications, although tranexamic acid, which is used in patients with acute bleeding for its antifibrinolytic effects, reportedly causes acute RCN in rare cases. An 82-year-old woman experienced gastrointestinal bleeding after endoscopic papillectomy of an ampullary adenoma. The bleeding was controlled with tranexamic acid administration; however, 4 days later, her urine volume decreased and she developed pulmonary edema and dyspnea. Serum creatinine levels increased from 0.8 to 3.9 mg/dL and dialysis was performed. Abdominal pelvic computed tomography with contrast enhancement revealed bilateral RCN with no renal cortex enhancement. Renal dysfunction and oliguria persisted and hemodialysis was continued. Clinicians must be aware that acute RCN can occur after tranexamic acid administration to control bleeding.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Oliguria
/
Edema Pulmonar
/
Ácido Tranexámico
/
Adenoma
/
Diálisis Renal
/
Creatinina
/
Diálisis
/
Disnea
/
Lesión Renal Aguda
/
Hemorragia
Límite:
Anciano
/
Aged80
/
Femenino
/
Humanos
/
Embarazo
Idioma:
Inglés
Revista:
Clinical Endoscopy
Año:
2017
Tipo del documento:
Artículo
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