Clinicopathologic characteristics and prognostic factors in adenocarcinoma of the uterine cervix / 대한산부인과학회지

ABSTRACT

OBJECTIVE: To evaluate clinicopathologic characteristics and prognostic factors in adenocarcinoma of the uterine cervix. METHODS: Medical records of patients with adenocarcinoma of the cervix who primarily underwent radical hysterectomy and pelvic lymphadenectomy (n=72) at A Hospital from August 1998 to July 2004 were retrospectively reviewed. Patients with stage IA1-IIB lesions were included in the study. Clinical and pathological data were reviewed and analyzed. RESULTS: Mean age at presentation was 46.5 years. The mean follow-up time for surviving patients was 35 months. The overall survival rate was 91.7% and disease free survival rate was 88.9%. Using univariate analysis, stage, lymph-vascular space invasion (LVSI), parametrial invasion, pelvic lymph node invasion and depth of stromal invasion were significant for survival, whereas grade, age, endometrial invasion were not significant. But using multivariate analysis, only stage and pelvic lymph node invasion remained significant independent predictors for survival. CONCLUSION: Our study demonstrates that survival rate is high for patients with early stage, after primary surgery. We found stage and pelvic lymph node invasion of significant prognostic value for survival in cervical adenocarcinoma.