Myelodysplastic Syndrome in a Renal Transplant Recipient Treated with Long-term Azathioprine / 대한신장학회잡지

ABSTRACT

A 39-year-old renal transplant recipient was admitted for evaluation of pancytopenia which developed gradually 10 months ago. He received renal transplantation 10 years ago and maintained relatively good renal function. Since 1 year before admission, he showed progressive decline of hematocrit, WBC count and platelet. Initial bone marrow biopsy showed erythroid hypoplasia, and second bone marrow biopsy revealed myelodysplasia. Clinical course was fatal. In conclusion, if patients with long term azathioprine treatment show progressive pancytopenia, one should suspect the possibility of myelodysplastic syndrome.