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Clinical and Histopathologic Findings on the Abnormal Liver Function Complicated with Kawasaki Disease / 대한소아소화기영양학회지
Korean Journal of Pediatric Gastroenterology and Nutrition ; : 47-55, 2000.
Artículo en Coreano | WPRIM | ID: wpr-112812
ABSTRACT

PURPOSE:

The aim of this research is to examine the abnormal liver function complicated with Kawasaki disease (KD) and to analyze its clinical characteristics and complications.

METHODS:

Ninty eight cases were diagnosed as having KD, among which thirty four cases had abnormal alanine aminotransferase (ALT) (>30 IU/L). These abnormal ALT cases were evaluated in terms of age and sex distribution, major symptoms, complications, laboratory and histopathologic findings.

RESULTS:

Male to female ratio was 2.4 1 and most patients (91.2%) were under 5 years of age. Cervical lymphadenopathy was observed in 3 cases (8.8%); and recurred cases were two (5.8%). Average fever duration was 8 days average length of hospitalization was 9 days; and average recovery period was 13 days. Immediately after admission, positive CRP was observed in 31 cases (91.2%), leukocytosis (>10,000/mm(3)) in 26 cases (76.0%), thrombocytosis (>450,000/mm(3)) in 7 cases (20.6%), and anemia (<10 gm/dl) in 7 cases (20.6%), respectively. GB hydrops or cholecystitis were noted in 3 cases (8.8%) abnormal ECG finding in 1 case (2.9%), coronary dilatation or aneurysm in 2 cases (5.9%). Liver biopsy was done in four cases and revealed mild infiltration of lymphocytes on the portal area and mild bile duct proliferations.

CONCLUSION:

The abnormal liver function was noted in 34.7% of KD patients, and subsided all within one month. But the liver function test should be checked closely in patients of the abnormal liver function test complicated with KD despite of its good prognosis.
Asunto(s)

Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Asunto principal: Pronóstico / Trombocitosis / Conductos Biliares / Biopsia / Linfocitos / Colecistitis / Distribución por Sexo / Alanina Transaminasa / Dilatación / Edema Tipo de estudio: Estudio diagnóstico / Estudio pronóstico Límite: Femenino / Humanos / Masculino Idioma: Coreano Revista: Korean Journal of Pediatric Gastroenterology and Nutrition Año: 2000 Tipo del documento: Artículo

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Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Asunto principal: Pronóstico / Trombocitosis / Conductos Biliares / Biopsia / Linfocitos / Colecistitis / Distribución por Sexo / Alanina Transaminasa / Dilatación / Edema Tipo de estudio: Estudio diagnóstico / Estudio pronóstico Límite: Femenino / Humanos / Masculino Idioma: Coreano Revista: Korean Journal of Pediatric Gastroenterology and Nutrition Año: 2000 Tipo del documento: Artículo