Diagnosis of Tuberculous Cervical Lymphadenitis Using Polymerase Chain Reaction / 결핵
Tuberculosis and Respiratory Diseases
;
: 35-41, 1995.
Artículo
en Coreano
| WPRIM
| ID: wpr-113086
ABSTRACT
BACKGROUND:
Tuberculous cervical lymphadenitis can be diagnosed by clinical findings, chest X-ray, Mantoux test, but confirmed only by excisional biopsy. The polymerase chain reaction(PCR) is now widely applied to test very small amount of pathogen and would be used to detect Mycobacterium tuberculosis in biopsied tissues and fine needle aspirates.METHOD:
We carried out the PCR using IS-1 and IS-2 primers in 16 samples from tuberculous cervical lymphadenitis patients, and 13 samples from non-tuberculous cervical lymphadenopathy patients. Acid fast staining and culture for Mycobacterium were all negative.RESULTS:
All of 8 pathologically confirmed tuberculous cervical lymphadenitis samples showed positive PCR results, and of 5/8 clinically diagnosed samples were positive. None of 6 pathologically excluded samples were positive, and among 7 clinically undiagnosed samples 2 showed positive PCR results.CONCLUSION:
In patients with suspected tuberculous cervical lymphadenitis, PCR could be used to detect Mycobacterium tuberculosis using biopsied tissues and even fine needle aspirates with good sensitivity and specificity.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Tórax
/
Biopsia
/
Reacción en Cadena de la Polimerasa
/
Sensibilidad y Especificidad
/
Biopsia con Aguja Fina
/
Diagnóstico
/
Linfadenitis
/
Enfermedades Linfáticas
/
Mycobacterium
/
Mycobacterium tuberculosis
Tipo de estudio:
Estudio diagnóstico
Límite:
Humanos
Idioma:
Coreano
Revista:
Tuberculosis and Respiratory Diseases
Año:
1995
Tipo del documento:
Artículo
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