Correlation of Clinical Progress and Serum Prostate Specific Antigen in the Treatment of Chronic Prostatitis / 대한비뇨기과학회지
Korean Journal of Urology
;
: 974-977, 2006.
Artículo
en Coreano
| WPRIM
| ID: wpr-114225
ABSTRACT
Purpose:
We compared the baseline and post-treatment serum prostate specific antigen levels (s-PSA), the expressed prostatic secretion (EPS) and the chronic prostatitis symptom index (CPSI). We wanted to determine whether the serum PSA level could be used as a biochemical marker for checking the progress of patients with chronic prostatitis. Materials andMethods:
Of the patients who diagnosed with chronic prostatitis, we respectively reviewed the records of 48 men who were under 50 years old and who presented with a serum PSA level lower than 4ng/ ml (group P). As a control group (group N), we used the s-PSA data obtained from 2,787 men under 50 years old who had no evidence for lower urinary infection, and these men were seen at a serial screening program of a primary health clinic. After the treatment with antibiotics and nonsteroidal anti-inflammatory agents, the serum PSA and EPS were rechecked every 4 weeks. The National Institutes of Health (NIH)-CPSI scores were rechecked after 8 weeks.Results:
There are no different at mean age (group P vs N; 41.1 vs 41.1 years old). The baseline average serum PSA in group P was 1.53+/-0.73 ng/ml, and that in group N was 0.85 0.81ng/ml; the difference was significant (p=0.001). After 8 weeks of treatment, the average post-treatment serum PSA level was significantly decreased to 1.22+/-0.59ng/ml (p<0.05) and the leukocyte count in the EPS was also significantly decreased (p<0.05). The total NIH-CPSI score was significantly improved (p<0.05).Conclusions:
These data suggest that serum PSA is increased in chronic prostatitis patients. Antibiotics and nonsteroidal anti-inflammatory treatment can relief patients' symptoms as well as decrease the serum PSA for chronic prostatitis after 8 weeks. Therefore, serum PSA could be used as a diagnostic factor in determining the patients' progress with employing the CPSI score and EPS results.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Próstata
/
Prostatitis
/
Biomarcadores
/
Antiinflamatorios no Esteroideos
/
Tamizaje Masivo
/
Antígeno Prostático Específico
/
Recuento de Leucocitos
/
Antibacterianos
Tipo de estudio:
Estudio pronóstico
/
Estudio de tamizaje
Límite:
Humanos
/
Masculino
Idioma:
Coreano
Revista:
Korean Journal of Urology
Año:
2006
Tipo del documento:
Artículo
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