A Case of Statin-Induced Interstitial Pneumonitis due to Rosuvastatin / 결핵및호흡기질환
Tuberculosis and Respiratory Diseases
;
: 281-285, 2015.
Artículo
en Inglés
| WPRIM
| ID: wpr-114235
ABSTRACT
Statins lower the hyperlipidemia and reduce the incidence of cardiovascular events and related mortality. A 60-year-old man who was diagnosed with a transient ischemic attack was started on acetyl-L-carnitine, cilostazol, and rosuvastatin. After rosuvastatin treatment for 4 weeks, the patient presented with sudden onset fever, cough, and dyspnea. His symptoms were aggravated despite empirical antibiotic treatment. All infectious pathogens were excluded based on results of culture and polymerase chain reaction of the bronchoscopic wash specimens. Chest radiography showed diffuse ground-glass opacities in both lungs, along with several subpleural ground-glass opacity nodules; and a foamy alveolar macrophage appearance was confirmed on bronchoalveolar lavage. We suspected rosuvastatin-induced lung injury, discontinued rosuvastatin and initiated prednisolone 1 mg/kg tapered over 2weeks. After initiating steroid therapy, his symptoms and radiologic findings significantly improved. We suggest that clinicians should be aware of the potential for rosuvastatin-induced lung injury.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Acetilcarnitina
/
Tórax
/
Prednisolona
/
Radiografía
/
Ataque Isquémico Transitorio
/
Reacción en Cadena de la Polimerasa
/
Incidencia
/
Mortalidad
/
Macrófagos Alveolares
/
Enfermedades Pulmonares Intersticiales
Tipo de estudio:
Estudio diagnóstico
/
Estudio de incidencia
/
Estudio pronóstico
Límite:
Humanos
Idioma:
Inglés
Revista:
Tuberculosis and Respiratory Diseases
Año:
2015
Tipo del documento:
Artículo
Similares
MEDLINE
...
LILACS
LIS