Diagnostic Efficiency of Peritoneal Fluid and Serum Lactate Dehydrogenase(LDH) in Ovarian Cancer Patients / 대한부인종양콜포스코피학회잡지
Korean Journal of Gynecologic Oncology and Colposcopy
;
: 217-224, 2001.
Artículo
en Coreano
| WPRIM
| ID: wpr-115192
ABSTRACT
OBJECTIVES:
We studied peritoneal fluid and serum LDH levels to identify patients with ovarian carcinoma and differentiate them from patients with benign ovarian tumor or other gynecological tumors.METHODS:
From July 1998 to May 1999, peritoneal fluid and serum LDH, serum CA-125 levels were measured in 95 patients 11 with ovarian carcinoma, 2 with borderline ovarian tumor, 45 with benign ovarian tumor, 2 with endometrial carcinoma, 21 with CIS, 7 with cervical cancer and 7 with uterine myoma.RESULTS:
Peritoneal fluid LDH and serum LDH and CA-125 levels in ovarian cancer patients were significantly higher than those in patients with benign ovarian tumor and other gynecological tumors(p<0.05). Peritoneal fluid LDH demonstrated higher sensitivity(100%) and greater diagnostic efficiency(86%) than serum LDH(73% and 84%, respectively) or serum CA-125.(82% and 83%, respectively)CONCLUSION:
Peritoneal fluid LDH, compared to serum LDH and serum CA-125, presented the greatest diagnostic efficiency in discriminating ovarian cancer from benign ovarian tumor and, therefore, it may be efficient as a biochemical marker in diagnosis of ovarian cancer, even in early stages of the disease.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Neoplasias Ováricas
/
Líquido Ascítico
/
Biomarcadores
/
Neoplasias del Cuello Uterino
/
Neoplasias Endometriales
/
Ácido Láctico
/
Diagnóstico
/
Leiomioma
Tipo de estudio:
Estudio diagnóstico
Límite:
Femenino
/
Humanos
Idioma:
Coreano
Revista:
Korean Journal of Gynecologic Oncology and Colposcopy
Año:
2001
Tipo del documento:
Artículo
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