Four Year Trend of Carbapenem-Resistance in Newly Opened ICUs of a University-Affiliated Hospital of South Korea / 결핵및호흡기질환
Tuberculosis and Respiratory Diseases
;
: 360-366, 2012.
Artículo
en Inglés
| WPRIM
| ID: wpr-116864
ABSTRACT
BACKGROUND:
Carbapenem-resistance is rapidly evolving among the pathogenic microbes in intensive care units (ICUs). This study aimed to determine annual trend of carbapenem-resistance in the ICU for 4 years, since the opening of a university-affiliated hospital in South Korea.METHODS:
From 2005 to 2008, microbial samples from consecutive 6,772 patients were screened in the ICU. Three hundred and ninety-seven patients (5.9%) and their first isolates of carbapenem-resistant pathogens were analyzed.RESULTS:
The percentage of patients infected with carbapenem-resistant organisms increased constantly during the initial three years (2.3% in 2005, 6.2% in 2006, 7.8% in 2007), then it declined to 6.5% in 2008. Acute Physiology and Chronic Health Evaluation (APACHE) III score at admission was 58.0+/-23.5, the median length of the ICU stay was 37 days, and the mortality rate was 37.5%. The sampling sites were endotracheal suction (67%), catheterized urine (17%), wound (6%) and others (10%). Bacteria with carbapenem-resistance were Pseudomonas aeruginosa (247 isolates, 62%), Acinetobacter baumannii (117 isolates, 30%), Enterobacteriaceae (12 isolates, 3%), and others (21, 5%). Of note, peak isolation of carbapenem-resistant microorganisms in medical ICU was followed by the same epidemic at surgical ICU.CONCLUSION:
Taken together, carbapenem-resistant pathogens are of growing concern in the ICU.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Pseudomonas aeruginosa
/
Succión
/
Bacterias
/
Carbapenémicos
/
APACHE
/
Farmacorresistencia Bacteriana
/
Acinetobacter baumannii
/
Enterobacteriaceae
/
República de Corea
/
Catéteres
Límite:
Humanos
País/Región como asunto:
Asia
Idioma:
Inglés
Revista:
Tuberculosis and Respiratory Diseases
Año:
2012
Tipo del documento:
Artículo
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