Oral Tolerance: Not Simple But more Complex
Immune Network
;
: 169-175, 2003.
Artículo
en Inglés
| WPRIM
| ID: wpr-116898
ABSTRACT
The intestinal immune system can discriminate between harmful and unharmful antigens and do not provoke productive immunity to unharmful antigen. Thus oral administration of antigen is one of classical methods for inducing antigen-specific immune tolerance in the periphery. Furthermore, oral tolerance has been investigated for the treatment of autoimmune disorders in human clinical trials. However, the detail mechanism of oral tolerance and contributing factors are not defined clearly at this time. Recent studies demonstrate unique types of immune cell that suppressing immune response, such as regulatory T cell and tolerogenic dendritic cell. This article reviews the factors involved in oral tolerance and discusses our current understanding base on the recent literatures and our works.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Células Dendríticas
/
Administración Oral
/
Sistema Inmunológico
/
Tolerancia Inmunológica
Límite:
Humanos
Idioma:
Inglés
Revista:
Immune Network
Año:
2003
Tipo del documento:
Artículo
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