Serotonin and pancreatic duct function
Journal of Korean Medical Science
;
: S27-S28, 2000.
Artículo
en Inglés
| WPRIM
| ID: wpr-117533
ABSTRACT
1. 5-HT inhibits spontaneous fluid secretion as well as stimulated secretion with secretin (cAMP mediated) or ACh (Ca2+ mediated) in the isolated guinea pig pancreatic ducts. 2. The inhibitory effect of 5-HT is reversible and is dependent on the concentration in the range 0.01-0.1 microM, which is much lower than those that affect intestinal motility and secretion. 3. The 5-HT3 receptor in duct cells appears to mediate the inhibitory effect of 5-HT. 4. [Ca2+]i is unlikely to mediate the inhibitory effect of 5-HT.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Conductos Pancreáticos
/
Vasodilatadores
/
Secretina
/
Acetilcolina
/
Serotonina
/
5-Metoxitriptamina
/
Calcio
/
Cobayas
/
Animales
Idioma:
Inglés
Revista:
Journal of Korean Medical Science
Año:
2000
Tipo del documento:
Artículo
Similares
MEDLINE
...
LILACS
LIS