Dioxins and Health: Human Exposure Level and Epidemiologic Evidences of Health Effects / 예방의학회지
Korean Journal of Preventive Medicine
; : 303-313, 2003.
Article
en Ko
| WPRIM
| ID: wpr-118011
Biblioteca responsable:
WPRO
ABSTRACT
General information is summarized, that is necessary to introduce a scientific assessment of the human health and exposure issue concerning dioxin and dioxin-like compound. Scientific literatures were reviewed to assess the background exposures to the dioxin-like compounds for normal residents. Epidemiologic studies were also reviewed to assess malignant and nonmalignant effects of dioxins. In 1997, the International Agency for Research on Cancer classified 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin (TCDD) as a human carcinogen, primarily based on occupational cohort studies. The US Environmental Protection Agency made the same decision in it's Draft Dioxin Reassessment. Epidemiologic evidences point to a generalized excess of all cancers, without any pronounced excess at specific sites. Reported non-cancer effects included a range of conditions affecting most systems. Among them, chloracne, elevation in gamma glutamyl transferase (GGT), and alterations in reproductive hormones are related to TCDD. Other adverse outcomes, such as lipid concentrations, diabetes, circulatory and heart diseases, immunologic disorders, neurobehavioral effects, and developmental outcomes require further study before their respective relationships to TCDD can be more definitively assessed.
Palabras clave
Texto completo:
1
Índice:
WPRIM
Asunto principal:
Transferasas
/
United States Environmental Protection Agency
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Agencias Internacionales
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Estudios Epidemiológicos
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Estudios de Cohortes
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Dioxinas
/
Cloracné
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Dibenzodioxinas Policloradas
/
Cardiopatías
Tipo de estudio:
Etiology_studies
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Incidence_studies
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Observational_studies
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Prognostic_studies
/
Risk_factors_studies
Límite:
Humans
Idioma:
Ko
Revista:
Korean Journal of Preventive Medicine
Año:
2003
Tipo del documento:
Article