Relationship between trabecular strength and three-dimensional architecture in the pig mandible using microcomputed tomography / 대한구강악안면방사선학회지

ABSTRACT

PURPOSE: To investigate the relationship between three-dimensional (3D) bone imaging parameters and trabecular strength in the mandible. MATERIALS AND METHODS: Bone specimens were obtained from the mandibles of five male pigs weighing around 110 kg each. Of those, 43 samples were selected for 3D analysis and measured by micro-computed tomography. The five morphometric parameters were trabecular thickness (Tb.Th), bone specific surface (BS/BV), percent bone volume (BV/TV), structure model index (SMI) and degree of anisotropy (DA). Through destructive mechanical testing, strength parameters were obtained. RESULTS: BV/TV, SMI, BS/BV, and Tb.Th showed significant correlations with strength parameters. DA did not show any correlation with the other parameters. In multiple linear regression analysis, BV/TV alone explained 43% of the variance in Young's modulus. By stepwise inclusion of SMI, the variance in the Young's modulus was better explained up to 52%. CONCLUSIONS: Predicting trabecular strength in the mandible through architectural analysis would be possible. Further study is needed to establish the tendency and variety of trabecular architecture and strength according to the locations within the mandible.