Effects of the Oral Administration of Mosapride Citrate on Capsule Endoscopy Completion Rate
Gut and Liver
;
: 339-343, 2012.
Artículo
en Inglés
| WPRIM
| ID: wpr-119852
ABSTRACT
BACKGROUND/AIMS:
In capsule endoscopy (CE), the capsule does not always reach the cecum within its battery life, which may reduce its diagnostic yield. We evaluated the effect of mosapride citrate, a 5-hydroxytryptamine-4 agonist that increases gastrointestinal motility, on CE completion.METHODS:
In a retrospective study, we performed univariate and multivariate analyses for 232 CE procedures performed at our hospital. To identify factors that affect CE completion, the following data were systematically collected gender, age, gastric transit time (GTT), nonsteroidal anti-inflammatory drug administration, previous abdominal surgery, hospitalization, use of a polyethylene glycol solution, use of mosapride citrate (10 mg), body mass index (BMI), and total recording time.RESULTS:
The univariate analysis showed that oral mosapride citrate, GTT, and BMI were associated with improved CE completion. Multivariate analyses showed that oral mosapride citrate (odds ratio [OR], 1.99; 95% confidence interval [CI], 1.01 to 3.91) and GTT (OR, 2.34; 95% CI, 1.13 to 4.87) were significant factors for improving the CE completion. Oral mosapride citrate significantly shortened the GTT and small bowel transit time (SBTT).CONCLUSIONS:
Oral mosapride citrate reduced the GTT and SBTT during CE and improved the CE completion rate.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Polietilenglicoles
/
Benzamidas
/
Índice de Masa Corporal
/
Ciego
/
Morfolinas
/
Administración Oral
/
Análisis Multivariante
/
Estudios Retrospectivos
/
Ácido Cítrico
/
Endoscopía Capsular
Tipo de estudio:
Estudio observacional
/
Estudio pronóstico
Idioma:
Inglés
Revista:
Gut and Liver
Año:
2012
Tipo del documento:
Artículo
Similares
MEDLINE
...
LILACS
LIS