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A Case of Successful Treatment of Refractory Synovitis Acne Pustulosis Hyperostosis Osteitis (SAPHO) Syndrome with Adalimumab / 영남의대학술지
Yeungnam University Journal of Medicine ; : 55-57, 2013.
Artículo en Inglés | WPRIM | ID: wpr-120054
ABSTRACT
Synovitis acne pustulosis hyperostosis osteitis (SAPHO) syndrome is a rare disease that involves the skin, bones and joints. It is thought to be caused by infection with low-toxicity bacteria and to be the result of reactive infectious osteitis. However, this hypothesis has not yet been clearly established. New SAPHO syndrome treatment methods are needed because the disease does not respond to treatment in many cases. In this paper, a case is reported of SAPHO syndrome with pain in the acromioclavicular joint and with squamous and pustular macules on the palms and soles. First, the patient was treated with aceclofenac, prednisolon and sulfasalazine for two weeks. However, the symptoms were not relieved, so methotrexate and pamidronate were added to the treatment. Since no improvement was seen after four weeks of treatment, adalimumab was prescribed. The skin lesions were relieved two weeks later, and the bone pain and arthralgia, four weeks later. No recurrence or adverse effects were observed at the 22-week follow-up.
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Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Asunto principal: Osteítis / Recurrencia / Sulfasalazina / Piel / Sinovitis / Bacterias / Articulación Acromioclavicular / Hiperostosis / Diclofenaco / Metotrexato Tipo de estudio: Estudio observacional / Estudio pronóstico Límite: Humanos Idioma: Inglés Revista: Yeungnam University Journal of Medicine Año: 2013 Tipo del documento: Artículo

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Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Asunto principal: Osteítis / Recurrencia / Sulfasalazina / Piel / Sinovitis / Bacterias / Articulación Acromioclavicular / Hiperostosis / Diclofenaco / Metotrexato Tipo de estudio: Estudio observacional / Estudio pronóstico Límite: Humanos Idioma: Inglés Revista: Yeungnam University Journal of Medicine Año: 2013 Tipo del documento: Artículo