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Genes Causing Familial Parkinson's Disease / 대한정신약물학회지
Korean Journal of Psychopharmacology ; : 29-37, 2008.
Artículo en Coreano | WPRIM | ID: wpr-120564
ABSTRACT
Extended treatment using specific medicines for Parkinson's disease (PD) or psychotic disorders often induces symptoms related to psychotic disorders or PD, respectively. PD is the second most common neurodegenerative disease. Most cases of PD occur sporadically, but approximately 5-10% of cases are inherited as familial PD (FPD). Identification of the genes responsible for FPD, as well as their function, is essential to clarify the pathogenic mechanism of PD. Recent genomic analyses using samples obtained from patients with FPD have mapped 13 PARK loci and have identified SNCA, LRRK2, parkin, PINK1, DJ-1, ATP13A2 and UCHL1 as genes causing PD in those loci. This review discusses the results of recent studies on these PD genes.
Asunto(s)

Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Asunto principal: Enfermedad de Parkinson / Trastornos Psicóticos / Enfermedades Neurodegenerativas Límite: Humanos Idioma: Coreano Revista: Korean Journal of Psychopharmacology Año: 2008 Tipo del documento: Artículo

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Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Asunto principal: Enfermedad de Parkinson / Trastornos Psicóticos / Enfermedades Neurodegenerativas Límite: Humanos Idioma: Coreano Revista: Korean Journal of Psychopharmacology Año: 2008 Tipo del documento: Artículo