Blood Chimerism in a Dizygotic Dichorionic Pregnancy / 대한진단검사의학회지
The Korean Journal of Laboratory Medicine
;
: 521-524, 2010.
Artículo
en Inglés
| WPRIM
| ID: wpr-120810
ABSTRACT
Blood chimerism in twins is known to occur through the transfer of hematopoietic stem cells between the fetuses via a common placenta. We present a case of blood chimerism in a dizygotic dichorionic twin pregnancy. The female twin was delivered at 34 weeks of gestation, and the male twin was stillborn. Pathologic examination confirmed dichorionic diamniotic placentas. The karyotype of the female child was obtained using peripheral blood sample, and it revealed a mixture of 46,XX and 46,XY cells (chi 46,XY[13]/46,XX[7]). FISH analysis performed on the buccal cells by using CEP X/Y probe (Abbott Molecular Inc., USA) revealed 100% XX signals (nuc ish Xcen(DXZ1x2)[500]). Gross examination of the external genitalia and abdominal ultrasonography revealed no definitive abnormal findings in relation to sex differentiation. When XX/XY chimerism is present in blood lymphocytes, careful examination of external genitalia and reproductive organs and further studies are required to detect chimerism in non-hematopoetic tissues. This is a rare case of blood chimerism in dichorionic placentas, in contrast to those in monochorionic placentas.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Gemelos Dicigóticos
/
Incompatibilidad de Grupos Sanguíneos
/
Fertilización In Vitro
/
Ultrasonografía Prenatal
/
Edad Gestacional
/
Hibridación Fluorescente in Situ
/
Quimerismo
/
Enfermedades en Gemelos
/
Cariotipificación
Tipo de estudio:
Estudio diagnóstico
Límite:
Adulto
/
Femenino
/
Humanos
/
Masculino
/
Recién Nacido
/
Embarazo
Idioma:
Inglés
Revista:
The Korean Journal of Laboratory Medicine
Año:
2010
Tipo del documento:
Artículo
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