Medullary Thyroid Carcinoma with Ectopic Adrenocorticotropic Hormone Syndrome
Endocrinology and Metabolism
;
: 96-100, 2014.
Artículo
en Inglés
| WPRIM
| ID: wpr-121034
ABSTRACT
Ectopic adrenocorticotropic hormone (ACTH) syndrome is caused most frequently by a bronchial carcinoid tumor or by small cell lung cancer. Medullary thyroid carcinoma (MTC) is a rare etiology of ectopic ACTH syndrome. We describe a case of Cushing syndrome due to ectopic ACTH production from MTC in a 48-year-old male. He was diagnosed with MTC 14 years ago and underwent total thyroidectomy, cervical lymph node dissection and a series of metastasectomies. MTC was confirmed by the pathological examination of the thyroid and metastatic mediastinal lymph node tissues. Two years after his last surgery, he developed Cushingoid features, such as moon face and central obesity, accompanied by uncontrolled hypertension and new-onset diabetes. The laboratory results were compatible with ectopic ACTH syndrome. A bilateral adrenalectomy improved the clinical and laboratory findings that were associated with Cushing syndrome. This is the first confirmed case of ectopic ACTH syndrome caused by MTC in Korea.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Glándula Tiroides
/
Tiroidectomía
/
Síndrome de ACTH Ectópico
/
Neoplasias de la Tiroides
/
Tumor Carcinoide
/
Hormona Adrenocorticotrópica
/
Adrenalectomía
/
Síndrome de Cushing
/
Carcinoma Pulmonar de Células Pequeñas
/
Obesidad Abdominal
Límite:
Humanos
/
Masculino
País/Región como asunto:
Asia
Idioma:
Inglés
Revista:
Endocrinology and Metabolism
Año:
2014
Tipo del documento:
Artículo
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