Neuroendocrine Effects in Occupational Solvents Exposure / 대한산업의학회지
Korean Journal of Occupational and Environmental Medicine
;
: 362-374, 1995.
Artículo
en Coreano
| WPRIM
| ID: wpr-121264
ABSTRACT
Long term occupational exposure to solvent mixtures may cause adverse effects to the central nervous system with neurobehavioral symptoms. And some organic solvents have been suggested to cause impairment of tuberoinfundibular dopaminergic activity and neurochemical mechanisms controlling pituitary secretion. For the purpose of assessing neuroendocrine effects in occupational solvents exposure, hormonal study settings (shoes-manufacturing industry & fishing products industry) and compared with nonexposed controls (33men, 85women). Male workers exposed to solvent mixtures had significantly lower plasma level of follicle-stimulating hormone (FSH) than nonexposed male controls. While female workers exposed to solvent mixtures had significantly lower plasma levels of growth hormone (GH), and thyroid-stimulating hormone (TSH) than nonexposed female controls. The results of significant decrease in plasma concentrations of pituitary hormones (FSH, GH, and TSH) in workers exposed solvent mixtures indicate that occupational exposure to solvent mixtures may induce neuroendocrine effects through an effect on hypothalamic pituitary axis.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Hormonas Hipofisarias
/
Plasma
/
Solventes
/
Vértebra Cervical Axis
/
Hormona del Crecimiento
/
Tirotropina
/
Sistema Nervioso Central
/
Exposición Profesional
/
Hormona Folículo Estimulante
Límite:
Femenino
/
Humanos
/
Masculino
Idioma:
Coreano
Revista:
Korean Journal of Occupational and Environmental Medicine
Año:
1995
Tipo del documento:
Artículo
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