Antimicrobial Susceptibility Patterns of Legionella isolates in the Environment and in Patients / 대한진단검사의학회지
The Korean Journal of Laboratory Medicine
;
: 28-33, 2010.
Artículo
en Coreano
| WPRIM
| ID: wpr-121790
ABSTRACT
BACKGROUND:
Antimicrobial susceptibility of Legionella spp. has rarely been studied in Korea. Therefore, we aimed to determine the susceptibility of Legionella spp. to various antibiotics.METHODS:
We assessed the antimicrobial susceptibility of 66 environmental and clinical Legionella isolates collected between January 2001 and December 2008 from Korea and Japan. The minimum inhibitory concentrations (MICs) of 6 antibiotics, namely, azithromycin, ciprofloxacin, clarithromycin, clindamycin, gatifloxacin, and gemifloxacin were determined by the broth microdilution method using buffered starch yeast extract broth.RESULTS:
The MIC ranges of the 6 antibiotics used against the Legionella isolates were as follows 0.004-0.062 microgram/mL (azithromycin), 0.002-0.5 microgram/mL (ciprofloxacin), 0.004-0.5 microgram/mL (clarithromycin), 0.12-4 microgram/mL (clindamycin), 0.002-0.12 microgram/mL (gatifloxacin), and 0.008-1 microgram/mL (gemifloxacin).CONCLUSIONS:
Legionella spp. isolates from Korea and Japan were most susceptible to gatifloxacin. Azithromycin, clarithromycin, ciprofloxacin, and gemifloxacin were also effective for treating legionellosis.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Legionelosis
/
Legionella
/
Clindamicina
/
Ciprofloxacina
/
Pruebas de Sensibilidad Microbiana
/
Claritromicina
/
Azitromicina
/
Fluoroquinolonas
/
Farmacorresistencia Bacteriana
/
Antibacterianos
Límite:
Humanos
Idioma:
Coreano
Revista:
The Korean Journal of Laboratory Medicine
Año:
2010
Tipo del documento:
Artículo
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