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Differentiation between Benign and Malignant Solid Thyroid Nodules Using an US Classification System
Korean Journal of Radiology ; : 559-567, 2011.
Artículo en Inglés | WPRIM | ID: wpr-121840
ABSTRACT

OBJECTIVE:

To evaluate the diagnostic accuracy of a new ultrasound (US) classification system for differentiating between benign and malignant solid thyroid nodules. MATERIALS AND

METHODS:

In this study, we enrolled 191 consecutive patients who received real-time US and subsequent US diagnoses for solid thyroid nodules, and underwent US-guided fine-needle aspiration. Each thyroid nodule was prospectively classified into 1 of 5 diagnostic categories by real-time US "malignant," "suspicious for malignancy," "borderline," "probably benign," and "benign". We evaluated the diagnostic accuracy of thyroid US and the cut-off US criteria by comparing the US diagnoses of thyroid nodules with cytopathologic results.

RESULTS:

Of the 191 solid nodules, 103 were subjected to thyroid surgery. US categories for these 191 nodules were malignant (n = 52), suspicious for malignancy (n = 16), borderline (n = 23), probably benign (n = 18), and benign (n = 82). A receiver-operating characteristic curve analysis revealed that the US diagnosis for solid thyroid nodules using the 5-category US classification system was very good. The sensitivity, specificity, positive and negative predictive values, and accuracy of US diagnosis were 86%, 95%, 91%, 92%, and 92%, respectively, when benign, probably benign, and borderline categories were collectively classified as benign (negative).

CONCLUSION:

The diagnostic accuracy of thyroid US for solid thyroid nodules is high when the above-mentioned US classification system is applied.
Asunto(s)

Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Asunto principal: Neoplasias de la Tiroides / Valor Predictivo de las Pruebas / Sensibilidad y Especificidad / Nódulo Tiroideo / Ultrasonografía Intervencional / Citodiagnóstico / Biopsia con Aguja Fina / Diagnóstico Diferencial Tipo de estudio: Estudio diagnóstico / Estudio pronóstico Límite: Femenino / Humanos / Masculino Idioma: Inglés Revista: Korean Journal of Radiology Año: 2011 Tipo del documento: Artículo

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Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Asunto principal: Neoplasias de la Tiroides / Valor Predictivo de las Pruebas / Sensibilidad y Especificidad / Nódulo Tiroideo / Ultrasonografía Intervencional / Citodiagnóstico / Biopsia con Aguja Fina / Diagnóstico Diferencial Tipo de estudio: Estudio diagnóstico / Estudio pronóstico Límite: Femenino / Humanos / Masculino Idioma: Inglés Revista: Korean Journal of Radiology Año: 2011 Tipo del documento: Artículo