Stem Cell Transplantation in Retinitis Pigmentosa Patients
Journal of the Korean Ophthalmological Society
;
: 1954-1959, 2006.
Artículo
en Coreano
| WPRIM
| ID: wpr-123163
ABSTRACT
PURPOSE:
This study was to evaluate the effect of stem cell transplantation into the sub-retinal space in retinitis pigmentosa (RP) patients for improving their visual acuity. RP is a progressive hereditary disease that leads to the blindness, and there is no reliable treatment for recover the disease until now.METHODS:
The author transplanted mesenchymal stem cell extracted from umbilical cord blood into the sub-retina of four RP patients recommended by Korea RP association, and checked the changes of their visual acuity and electroretinograms.RESULTS:
There was no obvious improvement in their visual acuity and elecroretinograms compared with preoperative state. Two patients, however, experienced slight improvements of their color sense and peripheral visual fields, and slight decrease of photophobia. Although there were no any obvious complications in relation to the stem cell transplantation, surgical procedures developed complications such as vitreous hemorrhage and retinal detachment.CONCLUSIONS:
Mesenchymal stem cell derived from umbilical cord blood could not improve visual acuity and electroretinogram of RP patients.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Retinitis
/
Células Madre
/
Hemorragia Vítrea
/
Desprendimiento de Retina
/
Agudeza Visual
/
Campos Visuales
/
Retinitis Pigmentosa
/
Ceguera
/
Estrabismo
/
Fotofobia
Límite:
Humanos
País/Región como asunto:
Asia
Idioma:
Coreano
Revista:
Journal of the Korean Ophthalmological Society
Año:
2006
Tipo del documento:
Artículo
Similares
MEDLINE
...
LILACS
LIS