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Aloe vera gel and thyroid hormone cream may improve wound healing in Wistar rats / 대한해부학회지
Anatomy & Cell Biology ; : 170-177, 2012.
Artículo en Inglés | WPRIM | ID: wpr-125840
ABSTRACT
Therapeutic effects of various treatment options in wound healing have been one of the most controversial issues in surgical science. The present study was carried out to examine and compare the effects of Aloe vera gel, thyroid hormone cream and silver sulfadiazine cream onsutured incisions in Wistar rats. In a randomized controlled trial, thirty-six Wistar male rats, 250 to 300 g, received surgical incisions followed by topical application of Aloe vera gel, thyroid hormone cream and silver sulfadiazine 1%. To assess the efficacy of each treatment technique, a histological approach was used to evaluate the mean number of fibroblasts, macrophages, neutrophils, blood vessel sections and thickness of the regenerating epithelium and dermis on days 4, 7 and 14. Re-epithelialization and angiogenesis were significantly improved in Aloe vera gel group compared with the other treatments while thyroid hormone cream had positive effects on day 4 (P< or =0.05). Topical administration of Aloe vera gel is recommended as the treatment of choice for surgical incisions.
Asunto(s)

Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Asunto principal: Sulfadiazina de Plata / Glándula Tiroides / Hormonas Tiroideas / Cicatrización de Heridas / Vasos Sanguíneos / Administración Tópica / Ratas Wistar / Dermis / Epitelio / Aloe Tipo de estudio: Ensayo Clínico Controlado Límite: Animales / Humanos / Masculino Idioma: Inglés Revista: Anatomy & Cell Biology Año: 2012 Tipo del documento: Artículo

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Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Asunto principal: Sulfadiazina de Plata / Glándula Tiroides / Hormonas Tiroideas / Cicatrización de Heridas / Vasos Sanguíneos / Administración Tópica / Ratas Wistar / Dermis / Epitelio / Aloe Tipo de estudio: Ensayo Clínico Controlado Límite: Animales / Humanos / Masculino Idioma: Inglés Revista: Anatomy & Cell Biology Año: 2012 Tipo del documento: Artículo