Efficacy of a Topical Gelatin-Thrombin Matrix Sealant in Reducing Postoperative Drainage Following Anterior Cervical Discectomy and Fusion
Asian Spine Journal
;
: 909-915, 2015.
Artículo
en Inglés
| WPRIM
| ID: wpr-126909
ABSTRACT
STUDY DESIGN:
Retrospective fusion level(s)-, age-, and gender-matched analysis.PURPOSE:
To determine whether the application of a topical gelatin-thrombin matrix sealant (Floseal) at the end of anterior cervical discectomy and fusion (ACDF) can reduce the amount of postoperative hemorrhage. OVERVIEW OF LITERATURE The effect of the matrix sealant in decreasing postoperative hemorrhage following ACDF has not been reported.METHODS:
Matrix sealant was (n=116, study group) or was not applied (n=58, control group) at the end of ACDF. Patients were selected by 12 matching criteria of fusion level(s), age, and gender. Seven parameters described below were compared between the two groups.RESULTS:
The total drain amount for the first 24 hours (8+/-9 versus 27+/-22 mL), total drain amount until the 8-hour drainage decreased to < or =10 mL (8+/-10 versus 33+/-26 mL), and the total drain amount until 6 AM on the first postoperative day (7+/-8 versus 24+/-20 mL) were significantly lower in the study group than the control group (all p<0.001). The time for the 8-hour drainage to decrease to < or =10 mL was significantly lower in the study group (10+/-5 versus 26+/-14 hours, p<0.001). The 8-hour drainage decreased to < or =10 mL on the operation day in most patients (88%) in the study group versus mostly on the first (48%) or second (33%) postoperative day in the control group (p<0.001). The total drain amount until 6 AM on the first postoperative day was 0 mL in 43% of patients in the study group and in 7% in the control group (p<0.001). No patient in either group required hematoma evacuation.CONCLUSIONS:
Application of the topical matrix sealant at the end of ACDF can significantly reduce the amount of postoperative hemorrhage.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Fusión Vertebral
/
Vértebras Cervicales
/
Drenaje
/
Estudios Retrospectivos
/
Discectomía
/
Hemorragia Posoperatoria
/
Hematoma
/
Hemostasis
Tipo de estudio:
Estudio observacional
Límite:
Femenino
/
Humanos
Idioma:
Inglés
Revista:
Asian Spine Journal
Año:
2015
Tipo del documento:
Artículo
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