A Morphologic Study on the Regeneration of Sciatic Nerve Replaced with Autogenous Skeletal Muscle in Rat / 대한정형외과연구학회지
Journal of Korean Orthopaedic Research Society
;
: 56-63, 2008.
Artículo
en Coreano
| WPRIM
| ID: wpr-126982
ABSTRACT
PURPOSE:
To investigate the morphological features of nerve regeneration in the rat sciatic nerve defect filled with autogenous skeletal muscle. MATERIALS ANDMETHODS:
We used thirty Sprague-Dawley rats with weight of 300g. Nerve segment of 1 cm was resected from the right sciatic nerve in the study group. After filling the defect with autogenous skeletal muscle, we sutured epineurium of the resected sicatic nerve. At twelve months after surgery, examination with light and transmission electron microscopies were performed on the specimens and left normal sciatic nerves. RESUTLS Many regenerating nerve fibers were detected along the muscle graft. The number of myelinated nerve fibers was significantly greater in regenerated nerves than in normal nerves, but the size of myelinated nerve fibers was smaller in regenerated nerves. Ultrastructural observations showed nerve fibers and Schwann cells between muscle fibers.CONCLUSION:
The light and transmission electron microscopy showed that a good morphological pattern of nerve regeneration in gap filled with skeletal muscle.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Nervios Periféricos
/
Regeneración
/
Células de Schwann
/
Nervio Ciático
/
Ratas Sprague-Dawley
/
Músculo Esquelético
/
Trasplantes
/
Microscopía Electrónica de Transmisión
/
Electrones
/
Luz
Límite:
Animales
Idioma:
Coreano
Revista:
Journal of Korean Orthopaedic Research Society
Año:
2008
Tipo del documento:
Artículo
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