Subconjunctival Juvenile Xanthogranuloma Involving the Limbus Associated with Neurofibromatosis
Journal of the Korean Ophthalmological Society
;
: 1733-1736, 2005.
Artículo
en Coreano
| WPRIM
| ID: wpr-127732
ABSTRACT
PURPOSE:
To report a case of isolated subconjunctival juvenile xanthogranuloma invading the corneal limbus in a patient with neurofibromatosis.METHODS:
A 2-year-old boy visited the hospital with a conjunctival yellow-brown, non-tender mass of the left eye, which had been found 2 months earlier. Anterior segment examination revealed a 9 x 7 mm-sized subconjunctival elevated mass with an ill-defined border, invading the supero-temporal limbus. Additional ophthalmic examinations did not show any abnormal findings. In the trunk and extremities, there were multiple soft nodules and brown macules. An excisional biopsy of the subconjunctival mass, histopathologic and immunohistochemical examinations were performed.RESULTS:
The mass was adhered to the episcleral tissue, without scleral or conjunctival involvement. The histological examination showed a granulomatous lesion consisting of multiple lipid-laden macrophages and other inflammatory cells. The immunohistochemical study showed positive staining for CD68 and negative staining for S100 protein. The multiple soft nodules and brown macules in the trunk and extremities were identified as neurofibromas and caf -au-lait macules by a dermatologist, and the patient was diagnosed with neurofibromatosis.CONCLUSIONS:
We report a rare case of subconjunctival juvenile xanthogranuloma involving the limbus, associated with neurofibromatosis.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Biopsia
/
Coloración Negativa
/
Limbo de la Córnea
/
Xantogranuloma Juvenil
/
Neurofibromatosis
/
Extremidades
/
Macrófagos
/
Neurofibroma
Tipo de estudio:
Estudio pronóstico
Límite:
Child, preschool
/
Humanos
/
Masculino
Idioma:
Coreano
Revista:
Journal of the Korean Ophthalmological Society
Año:
2005
Tipo del documento:
Artículo
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