Mucosal Restitution / 대한소화기학회지
The Korean Journal of Gastroenterology
;
: 409-412, 2006.
Artículo
en Coreano
| WPRIM
| ID: wpr-129851
ABSTRACT
The repair of superficially damaged intestinal epithelium is initiated by restitution. Restitution is the covering of damaged area by the movement of neighboring epithelial cells without cell proliferation. Phenotypic switching of cells (epithelial-mesenchymal transition) is necessary for the cell movement and this process is controlled by complex intracellular signaling pathways conducting dynamic remodeling of actin cytoskeleton. Restitution is regulated by a variety of cytokines and growth factors, and is modulated by integrin-dependent interactions with the extracellular matrix. Understanding the restitution process suggests several possible therapeutic strategies to enhance gastrointestinal wound healing.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Regeneración
/
Movimiento Celular
/
Mucosa Intestinal
Límite:
Humanos
Idioma:
Coreano
Revista:
The Korean Journal of Gastroenterology
Año:
2006
Tipo del documento:
Artículo
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