NK/T-cell Lymphoma Involving Multiple Organs in Renal Transplant Recipient / 대한신장학회잡지
Korean Journal of Nephrology
;
: 358-363, 2004.
Artículo
en Coreano
| WPRIM
| ID: wpr-133220
ABSTRACT
Posttransplant lymphoproliferative disorders (PTLDs) represent a potentially life-threatening complication following renal transplantation. Their incidence is usually low, in the range of 1-2%. The majority of PTLD is B cell origin and strongly associated with Epstein Barr virus (EBV). PTLD of T cell origin is uncommon and has a poor prognosis. We have experienced a case of NK/T cell lymphoma involving stomach, mesenteric lymph nodes, and heart after renal transplantation. The patient was 34 years old man who received renal transplant in 1999. He was admitted with a complaint of fever and pancytopenia for 2 weeks in 2003. Though antibiotic and antifungal treatment, fever and pancytopenia were continued. On the third hospital day, he present waterly diarrhea. We found multiple hemorrhagic erosions in the stomach by gastrofiberscopy and did biopsy there. Gastric mucosal biopsy showed infiltration by atypical cells between the mucosal glands and submucosal layer. The immunophenotype of these tumor cells were CD3+, UCHL+, and CD56+ and all negative for B cell markers. He was dead because of massive gastrointestinal bleeding after endoscopic biopsy of stomach. The autopsy revealed the widespreading of tumor cells involving heart and mesenteric lymph nodes.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Pancitopenia
/
Pronóstico
/
Autopsia
/
Estómago
/
Trasplante
/
Biopsia
/
Incidencia
/
Trasplante de Riñón
/
Herpesvirus Humano 4
/
Diarrea
Tipo de estudio:
Estudio de incidencia
/
Estudio pronóstico
Límite:
Adulto
/
Humanos
Idioma:
Coreano
Revista:
Korean Journal of Nephrology
Año:
2004
Tipo del documento:
Artículo
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