Two cases of SAPHO syndrome / 대한내과학회지
Korean Journal of Medicine
;
: S782-S787, 2003.
Artículo
en Coreano
| WPRIM
| ID: wpr-138910
ABSTRACT
We describe two cases of SAPHO syndrome with history of palmoplantar pustulosis and pain on the anterior chest wall and lower back area. The acronym SAPHO (synovitis, acne, pustulosis, hyperostosis and osteitis) syndrome includes a group of disorders characterized by bony lesions commonly involving the anterior chest wall and associated with skin manifestations. The skeletal manifestation is characterized by the association of inflammation and hyperostotic change, in the form of sternocostoclavicular hyperostosis, spondyloarthropathy and chronic recurrent multifocal osteomyelitis. Common cutaneous lesions include palmoplantar pustulosis, pustulotic psoriasis, and severe forms of acne. The pathogenesis remains elusive, but a link with seronegative spondyloarthropathy is probable. To date, the treatment is empirical. Nonsteroidal anti-inflammatory drugs are the first choice, and other drugs including corticosteroid, disease modifying antirheumatic drugs, pamidronate, and infliximab have been tried with some therapeutic benefit. SAPHO syndrome is a condition in the differential diagnosis of infectious or tumorous conditions of the bone. Early and proper diagnosis is important to avoid unnecessary investigations or treatments.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Osteomielitis
/
Psoriasis
/
Manifestaciones Cutáneas
/
Columna Vertebral
/
Hiperostosis
/
Hiperostosis Esternocostoclavicular
/
Acné Vulgar
/
Antirreumáticos
/
Síndrome de Hiperostosis Adquirido
/
Espondiloartropatías
Tipo de estudio:
Estudio diagnóstico
Idioma:
Coreano
Revista:
Korean Journal of Medicine
Año:
2003
Tipo del documento:
Artículo
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