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Histological Changes of Gastric Mucosa after Helicobacter pylori Eradication
The Korean Journal of Helicobacter and Upper Gastrointestinal Research ; : 229-234, 2013.
Artículo en Coreano | WPRIM | ID: wpr-140177
ABSTRACT
BACKGROUND/

AIMS:

The aim of this study was to evaluate whether Helicobacter pylori eradication could improve histologic findings of gastric mucosa. MATERIALS AND

METHODS:

One hundred thirty two H. pylori infected patients were evaluated for histologic findings. Biopsy specimens from antrum and corpus were taken before and 7 weeks after H. pylori eradication therapy. Before and after eradication, H. pylori status was determined by biopsy, rapid urease test and urea breath test. Histologic findings were classified as mild, moderate, or severe according to the updated Sydney classification.

RESULTS:

The scoring of H. pylori density, activity and gastric atrophy was found significantly decreased in H. pylori eradicated groups after 7 weeks, while no significant change was found in H. pylori non-eradicated groups. Intestinal metaplasia wasn't improved in neither H. pylori eradicated group or H. pylori non-eradicated group.

CONCLUSIONS:

It can be suggested that improvement of H. pylori density, activity and gastric atrophy may occur after eradication of H. pylori. To see the positive effects of eradication therapy, a longer follow-up duration might be needed.
Asunto(s)

Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Asunto principal: Atrofia / Urea / Ureasa / Biopsia / Pruebas Respiratorias / Estudios de Seguimiento / Helicobacter pylori / Helicobacter / Mucosa Gástrica / Metaplasia Tipo de estudio: Estudio observacional / Estudio pronóstico Límite: Humanos Idioma: Coreano Revista: The Korean Journal of Helicobacter and Upper Gastrointestinal Research Año: 2013 Tipo del documento: Artículo

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Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Asunto principal: Atrofia / Urea / Ureasa / Biopsia / Pruebas Respiratorias / Estudios de Seguimiento / Helicobacter pylori / Helicobacter / Mucosa Gástrica / Metaplasia Tipo de estudio: Estudio observacional / Estudio pronóstico Límite: Humanos Idioma: Coreano Revista: The Korean Journal of Helicobacter and Upper Gastrointestinal Research Año: 2013 Tipo del documento: Artículo